Depression

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Quick answer. Depression is more than low mood or a hard few days: it is a persistent low mood or loss of interest and pleasure, usually lasting at least two weeks, that affects sleep, energy, concentration, and how a person sees themselves and the future. It is common and treatable — talking therapies such as CBT help many people, and some also find antidepressant medication useful, which is a decision to discuss with a GP or qualified prescriber. If you ever have thoughts of suicide or feel unable to keep yourself safe, contact the emergency services (112 or 999), call the Samaritans free on 116 123, or Pieta on 1800 247 247.

Depression Guides and Support Routes

These newer guides help readers move from broad depression information into self-reflection, high-functioning depression, support options and therapy routes.

Depression Support: Understanding, Safety and Next Steps

When depression is part of life, people often need more than a symptom list. It can help to know where to find reliable information, what support routes exist in Ireland, and when personal professional help may be important.

If you might harm yourself or someone else, or you feel unable to stay safe, contact local emergency services or urgent mental-health support now. This page is not a crisis service or a substitute for diagnosis or personal medical advice. For source and review boundaries, see how this mental health information is written and reviewed and the disclaimer.

Depression is more than feeling sad or having a difficult week. It can bring a persistent heaviness that touches mood, energy, sleep, motivation, and the ability to find pleasure in things that usually matter. Many people live with it for months or years before seeking help, and many feel they should be able to manage alone. You do not have to.

Choose a depression route

Depression can show up as low mood, loss of interest, exhaustion, sleep change, postnatal distress, or more urgent symptoms. These routes separate common questions from help routes.

Information guides

Help and higher-risk symptoms

A depression, if it is not primarily a reaction to a life event, is called in psychiatry a major depressive disorder (MDD). It is a condition characterized by at least two weeks of low mood that is present across most situations.[1] It is often accompanied by low self-esteem, loss of interest in normally enjoyable activities, low energy, and psychological pain without a clear cause. There may also be false beliefs and – in the more severe cases – acoustic or visual hallucinations. Major depression needs to be differentiated from sadness. Depression often actually means the subjective absence of feelings, such as sadness. Those afflicted with depression often cannot feel themselves anymore as before, which can cause additional anxiety.

Three friends jumping in the air with balloons

Start here for depression

Depression can affect mood, energy, sleep, appetite, concentration, relationships, and hope. Use the route below that sounds closest to what is happening now, then return to the longer article for background and detail.

Expert sources and further reading

Reviewed May 3, 2026. This page is educational and cannot replace diagnosis, medical advice, psychotherapy, counselling, medication review, or emergency care. Sources differ by country because health systems and guidelines differ; if you are seeking personal care, use local professional advice and local urgent-support routes.

Key points

  • Depression can affect mood, energy, sleep, concentration, motivation, relationships, body sensations, and hope.
  • It is more than ordinary sadness, especially when symptoms persist, impair daily life, or make safety harder to maintain.
  • Low mood can overlap with anxiety, grief, trauma, stress, medical problems, medication effects, and relationship difficulties.
  • If you feel unable to keep yourself safe, seek immediate help rather than waiting for an appointment or website reply.

Useful next steps: Find help, depression support pathway, make an appointment.

Depression is common worldwide, but estimates vary by country, age group, measurement method, and whether studies measure symptoms, diagnosis, or service contact. For readers, the practical question is less the exact percentage and more whether low mood, loss of interest, hopelessness, sleep or appetite change, self-criticism, or loss of functioning is persisting and narrowing life. Current global and country-level resources are linked in the expert-source section above.

The many forms of depression

Depression can come in many forms and guises. A mental health professional can help you to identify more closely if you are suffering from depression and form which form. Some ups and downs are a normal part of life. Life does not come in a straight line, which is actually good news, because a straight line would mean that we miss out on the excitement, the feeling alive, that life also offers. However, if the lows, or the highs in those suffering from a bipolar condition, take on intensity or frequency that reduces your quality of life or ability to perform everyday tasks, you should consult a mental health professional.

Melancholia is sometimes seen as a mild form. The cliche image is sitting curled up by a window on a rainy day. Dysthymia is usually the term for episodes of depression that stay just below the clinical threshold. While major forms of depression can occur in one episode or in multiple episodes. Still, however intense it feels, talking to someone about it is usually a good idea, even in milder cases. The view from the outside can be helpful. We may be caught so much by our feeling low that it begins to feel normal. Good indications for depression are not just the feelings one experiences, which in severe forms of depression can be almost absent, but also one’s daily activities and interactions with others. This is where the view from the outside can be helpful. Some people have only one episode of depression in their life, some have episodes of depression separated by years in which they feel normal, while others have symptoms almost constantly. But in all these different forms, from the single case to the recurring depression, treatment is usually effective.

DSM-5 Diagnostic Criteria

The DSM-V, the Diagnostic and Statistical Manual of Mental Disorders in its 5th edition, published by the American Psychiatric Association outlines the following criteria for a diagnosis of depression. The individual must be experiencing five or more symptoms during the same 2-week period and at least one of the symptoms should be either (1) depressed mood or (2) loss of interest or pleasure.

  1. Depressed mood most of the day, nearly every day.
  2. Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day.
  3. Significant weight loss when not dieting or weight gain, or decrease or increase in appetite nearly every day.
  4. A slowing down of thought and a reduction of physical movement (observable by others, not merely subjective feelings of restlessness or being slowed down).
  5. Fatigue or loss of energy nearly every day.
  6. Feelings of worthlessness or excessive or inappropriate guilt nearly every day.
  7. Diminished ability to think or concentrate, or indecisiveness, nearly every day.
  8. Recurrent thoughts of death, without a specific plan, or a suicide attempt or a specific plan for committing suicide.

A diagnosis always needs to be carried out by a trained mental health professional.

Another form of depression is reactive depression, which occurs as part of a number of conditions, such as post-traumatic stress disorder (PTSD). I discuss these forms of depression within the articles on these conditions. For PTSD, for example, you may want to look at one of my articles on PTSD:

Suicidal Thoughts

Suicidal thoughts can be quite common when one feels low or helpless. However, it should always be taken seriously and a mental health professional should be consulted. It does not automatically one has to stay in a hospital. Rather, it should be seen as a sign that something needs to be done quickly to address the mental health condition and raise the quality of life. Between 2-7% of adults with major depression die by suicide [3] and up to 60% of people who die by suicide had depression or another mood disorder [4]. With the right treatment early enough most of these suicides could have been prevented. Unfortunately, access to healthcare, particularly in the mental health area, is not the same everywhere. But in any case, if you experience suicidal thoughts, you should consult a healthcare professional right away. You can always call and go to an A&E. If none is available quickly, then you should contact a suicide hotline while making arrangements to see a mental health professional in person as soon as possible. Many people have experienced suicidal thoughts in their life, and it can be a strong starting point for very successful therapy.

A Vicious Cycle

Many people with milder forms of depression eventually come out of an episode, either spontaneously or because they have a good support network, are able to manage their stress in life, look after their sleep hygiene, exercise (in healthy moderation), and meditate, for example. However, psychotherapy or counselling is helpful at all levels of depression, and it can help prevent another episode. The problem is that depression can lead to a vicious cycle. The consequences of depression on one’s social life, for example, can make it more difficult to get out of the depression. Major depressive disorder can negatively affect a person’s family, work or school life, sleeping or eating habits, and general health, which distances us from an important resource for better mental health, other people.

Causes

The cause is believed to be a combination of genetic, environmental, and psychological factors. [1] Risk factors include a family history of the condition, major life changes, certain medications, chronic health problems, and substance abuse. [1] [2] About 40% of the risk appears to be related to genetics. [2]

Some other common symptoms of depression

Major depression significantly affects a person’s family and personal relationships, work or school life, sleeping and eating habits, and general health. [7] Its impact on functioning and well-being has been compared to that of other chronic medical conditions such as diabetes. A person having a major depressive episode usually exhibits a very low mood, which pervades all aspects of life, and unhedonia, the inability to experience pleasure in activities that were formerly enjoyed. Depressed people may be preoccupied with, or ruminate over, thoughts and feelings of worthlessness, inappropriate guilt or regret, helplessness, hopelessness, and self-hatred. [8] In severe cases, depressed people may have symptoms of psychosis. These symptoms include delusions or, less commonly, hallucinations, usually unpleasant.[9]

Other symptoms of depression include

  • poor concentration and memory
  • withdrawal from social situations and activities
  • reduced sex drive, irritability,
  • insomnia
  • and thoughts of death or suicide (which requires immediate professional help).

Insomnia is a common symptom. In the typical pattern, a person wakes very early and cannot get back to sleep.[25] Hypersomnia, or oversleeping, can also happen.[25] Some antidepressants may also cause insomnia due to their stimulating effect.[26]

A depressed person may report multiple physical symptoms such as

  • fatigue
  • headaches, or
  • digestive problems.

Appetite often decreases, with resulting weight loss, although increased appetite and weight gain occasionally occur. Family and friends may notice that the person’s behavior is either agitated or lethargic.

Causes

 

The biopsychosocial model proposes that biological, psychological, and social factors all play a role in causing depression.

On the biological side, the monoamine hypothesis is still the predominant biological explanation of depression. The monoamines are serotonine, norepinephrine, and dopamine. The antidepressants act on the neurotransmitter levels or on the receptors.

Serotonin is hypothesized to regulate other neurotransmitter systems; decreased serotonin activity may allow these systems to act in unusual and erratic ways.[43] According to this “permissive hypothesis”, depression arises when low serotonin levels promote low levels of norepinephrine, another monoamine neurotransmitter.[44] Some antidepressants enhance the levels of norepinephrine directly, whereas others raise the levels of dopamine, a third monoamine neurotransmitter. These observations gave rise to the monoamine hypothesis of depression. In its contemporary formulation, the monoamine hypothesis postulates that a deficiency of certain neurotransmitters is responsible for the corresponding features of depression.

For further articles on depression on this site:

 

[1] HSE: clinical depression symptoms; NIMH: depression. Source links reviewed May 3, 2026.

[2] American Psychiatric Association (2013), Diagnostic and Statistical Manual of Mental Disorders (5th ed.), Arlington: American Psychiatric Publishing, pp. 160–168, ISBN 978-0-89042-555-8

[3] Richards, C. Steven; O’Hara, Michael W. (2014). The Oxford Handbook of Depression and Comorbidity. Oxford University Press. p. 254. ISBN 9780199797042.

[4] Lynch, Virginia A.; Duval, Janet Barber (2010). Forensic Nursing Science. Elsevier Health Sciences. p. 453. ISBN 0323066380.

[5] Global Burden of Disease Study 2013, Collaborators (22 August 2015). “Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.”. Lancet (London, England). 386 (9995): 743–800. doi:10.1016/S0140-6736(15)60692-4. PMID 26063472.

[6] Kessler, RC; Bromet, EJ (2013). “The epidemiology of depression across cultures.”. Annual review of public health. 34: 119–38. doi:10.1146/annurev-publhealth-031912-114409. PMC 4100461. PMID 23514317.

[7] Depression (PDF). National Institute of Mental Health (NIMH).

[8] American Psychiatric Association 2000a, p. 349

[9] American Psychiatric Association 2000a, p. 412

© 2012, 2016 Dr Christian Jonathan Haverkampf. All rights reserved.

jonathanhaverkampf@gmail.com

Psychotherapy & Counselling, Communication, Medicine (Psychiatry); Dublin, Ireland

For psychotherapy, counselling and communication coaching visit jonathanhaverkampf.com, www.jonathan-haverkampf.com, www.wordnets.com.

This article is solely a basis for academic discussion and no medical advice can be given in this article, nor should anything herein be construed as advice. Always consult a professional if you believe you might suffer from a physical or mental health condition.

Trademarks belong to their respective owners. They have not been checked.

About this resource

This page is public educational information about depression and related difficulties. It is not a diagnosis, emergency response, medication advice, or substitute for care from a qualified professional.

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Related Guide: Social Rhythm Therapy

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Loss Of Interest And Depression

The anhedonia guide gives readers a dedicated route for loss of interest, emotional flatness, and reduced pleasure, with careful boundaries around depression, burnout, grief, trauma, medication effects, and medical review.

Related mood reading

Some readers also find this related guide useful when mood changes are part of the picture.

Eating Disorders and Support

Eating disorders often co-occur with depression and anxiety. The dedicated guide explains anorexia, bulimia, binge eating disorder, and where to get specialist help in Ireland.

Frequently asked questions

What is depression?

Depression is a common mental health condition involving persistent low mood and/or loss of interest or pleasure, usually for at least two weeks, together with changes in sleep, appetite, energy, concentration, and self-worth. It is more than ordinary sadness, it is not a sign of weakness, and it is treatable.

What are the common symptoms of depression?

Symptoms can include low or flat mood, loss of interest or pleasure, tiredness or low energy, changes in sleep and appetite, difficulty concentrating or making decisions, feelings of worthlessness or guilt, hopelessness, and sometimes thoughts of death or self-harm. People can experience depression differently.

When should I seek help for depression?

It can help to speak with a GP, psychotherapist, or counsellor when low mood lasts more than about two weeks, keeps returning, or interferes with daily life. Any thoughts of suicide or self-harm are a reason to seek help straight away.

What helps with depression?

Many people are helped by talking therapies such as cognitive behavioural therapy (CBT), interpersonal therapy, and other psychotherapeutic approaches, along with steps like activity, routine, and social connection. Some also find antidepressant medication useful, which is a decision to discuss with a GP or a qualified prescriber. You can read about depression therapy and counselling in Dublin and online. The right combination depends on the person.

When should I get urgent help for depression?

Seek urgent help if you have thoughts of suicide or self-harm, feel unable to keep yourself safe, or are unable to cope. In Ireland you can contact the emergency services on 112 or 999, call the Samaritans free on 116 123 at any time, or Pieta on 1800 247 247. You can also use HSE urgent mental health support.

Getting Help in Dublin and Across Ireland

Dr Jonathan Haverkampf is a psychotherapist and counsellor based in Dublin, Ireland, offering sessions in central Dublin and online across Ireland. If you would like support, these are some of the routes available, including free and low-cost options.

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