neuroscience

Anxiety and the Brain: The Forebrain’s Role in Social Decisions Unveiled

Researchers discovered that anxious individuals utilize a less optimal region of the forebrain when navigating socially challenging situations compared to their non-anxious counterparts. This was determined through brain scans that mapped regions active during simulated social scenarios.

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From fear of falling to choking under pressure: A predictive processing perspective of disrupted motor control under anxiety

Publication date: May 2023Source: Neuroscience & Biobehavioral Reviews, Volume 148Author(s): D.J. Harris, S. Wilkinson, T.J. Ellmers

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Consensus design of a calibration experiment for human fear conditioning

Publication date: May 2023Source: Neuroscience & Biobehavioral Reviews, Volume 148Author(s): Dominik R. Bach, Juliana Sporrer, Rany Abend, Tom Beckers, Joseph E. Dunsmoor, Miquel A. Fullana, Matthias Gamer, Dylan G. Gee, Alfons Hamm, Catherine A. Hartley, Ryan J. Herringa, Tanja Jovanovic, Raffael Kalisch, David C. Knight, Shmuel Lissek, Tina B. Lonsdorf, Christian J. Merz, Mohammed Milad, Jayne Morriss, Elizabeth A. Phelps

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Etiology of anxious and fearful behavior in juvenile neuronal ceroid lipofuscinosis (CLN3 disease)

… During the terminal phase, the cognitive developmental age of JNCL patients is below 2 years. At this stage of mental development individuals act primarily from a concrete world of consciousness and do not have the cognitive ability to encounter a normal anxiety response. Instead, they experience the evolutionary basic emotion of fear, and as

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How Prozac Increases Brain Plasticity

Fluoxetine (Prozac), a common antidepressant, was found to enhance the erasure of learned fear responses and facilitate spatial pattern learning in mice. The study also found the TrkB receptor in PV+ interneurons plays a crucial role in these effects, which may offer new possibilities for the development of psychiatric treatments targeting brain plasticity.

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Abnormal focal segments in left uncinate fasciculus in adults with obsessive–compulsive disorder

Although the specific role of the uncinate fasciculus (UF) in emotional processing in patients with obsessive–compulsive disorder (OCD) has been investigated, the exact focal abnormalities in the UF have not been identified. The aim of the current study was to identify focal abnormalities in the white matter (WM) microstructure of the UF and to determine

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Computational Mechanisms of Addiction and Anxiety: A Developmental Perspective

Biological Psychiatry, Volume 93, Issue 8, 2023 Apr 15, Pages 739-750 | Goldway, Noam; Eldar, Eran; Shoval, Gal;…AbstractA central goal of computational psychiatry is to identify systematic relationships between transdiagnostic dimensions of psychiatric symptomatology and the latent learning and decision-making computations that inform individuals’ thoughts,…

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