Researchers discovered that anxious individuals utilize a less optimal region of the forebrain when navigating socially challenging situations compared to their non-anxious counterparts. This was determined through brain scans that mapped regions active during simulated social scenarios.
Fluoxetine (Prozac), a common antidepressant, was found to enhance the erasure of learned fear responses and facilitate spatial pattern learning in mice. The study also found the TrkB receptor in PV+ interneurons plays a crucial role in these effects, which may offer new possibilities for the development of psychiatric treatments targeting brain plasticity.
Mood and anxiety disorders are believed to stem from an imbalance among neurons in the brain’s emotional hubs instead of areas responsible for higher thought processes. They are situated in the frontal lobe, which is said to be the most recently evolved part of our brains. Furthermore, evidence shows that the brain mechanisms engaged during