Anxiety and Medication

Can We Unlearn Fear?

Click here for the article published by Psychology Today. How is fear stored in the brain? And why may psychedelic therapies be able to help? Continue reading … Disclaimer: The content of this article has not been checked or verified. Proceed at your own risk.

Preoperative state anxiety predicts postoperative health-related quality of life: A prospective observational study on patients undergoing lung cancer surgery

ObjectiveImproving quality of life (QOL) after surgery is very important. Recently, preoperative anxiety has been suggested to predict postoperative health-related (HR) QOL, however the accuracy of anxiety measurement remains problematic. We examined the relationship between preoperative anxiety level and postoperative HRQOL using qualitative and quantitative assessment of anxiety.MethodWe used a detailed anxiety assessment to quantitatively investigate preoperative anxiety as a predictor of postoperative HRQOL in lung cancer patients. Fifty one patients who underwent surgery for lung cancer were included. They were assessed four times: on admission, on discharge, 1 month after surgery, and 3 months after surgery. Anxiety was measured separately as “state anxiety” and “trait anxiety” using the State–Trait Anxiety Inventory, and HRQOL was measured using the EuroQol 5 dimension 5-level.ResultsThe HRQOL decreased at discharge and gradually recovered over time, reaching the same level at 3 months after surgery as at admission. HRQOL score was lower at discharge than at pre-surgery and 3 months after the surgery (p 

Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain

Conditions:   Prostate Disease;   Malignancy;   Benign Prostatic Hyperplasia;   Prostate Cancer;   Prostate Adenocarcinoma;   Anxiety and Fear;   PainInterventions:   Drug: Self-Administered Nitrous Oxide;   Other: OxygenSponsors:   Beth Israel Deaconess Medical Center;   Brigham and Women’s HospitalCompleted

Classic Psychedelic Use and Mechanisms of Mental Health: Exploring the Mediating Roles of Spirituality and Emotion Processing on Symptoms of Anxiety, Depressed Mood, and Disordered Eating in a Community Sample

Journal of Humanistic Psychology, Ahead of Print. A resurgence of research has begun to systematically examine the relationship between psychedelic use and mental health and well-being. Although preliminary findings examining the therapeutic value of these substances show promise, the mechanisms through which psychedelic use may predict reduced mental distress remain poorly understood. To this end, we surveyed a community sample of individuals (n = 159) who endorsed lifetime psychedelic use to examine relationships among psychedelic use and self-reported spirituality, difficulties in emotion regulation, and symptoms of mental health issues. Results revealed a pathway through which classic psychedelic use predicted greater spirituality, which in turn predicted better emotion regulation, ultimately predicting lower levels of anxiety, depressed mood, and disordered eating. These results contribute to our understanding of potential mechanisms of change with respect to psychedelics and mental health. They also add to the growing body of literature pointing to the healing effects of the cultivation of spirituality and emotion regulation as separate and related constructs.

How Prozac Increases Brain Plasticity

Click here for the article published by Neurocience News. Fluoxetine (Prozac), a common antidepressant, was found to enhance the erasure of learned fear responses and facilitate spatial pattern learning in mice. The study also found the TrkB receptor in PV+ interneurons plays a crucial role in these effects, which may offer new possibilities for the …

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