Pharmacokinetics

Pharmacokinetics describes the processes that take place in the interaction between an organism and a chemical substance. There are four processes, which are often also represented as five:

Liberation: the drug is released from the pharmaceutical formulation

Absorption: the substance enters the blood circulation.

Distribution: the substance disperses throughout the fluids and tissues of the body.

Metabolism (Biotransformation): the parent compound is transformed into daughter metabolites

Excretion: the metabolites are excreted from the body

Elimination can be split into Metabolism and Excretion, which then yields five rather than four processes.

┬ę 2018 Christian Jonathan Haverkampf

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