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Consensus design of a calibration experiment for human fear conditioning

Leave a Comment / Fear Research, Fear Treatment, News /

Publication date: May 2023Source: Neuroscience & Biobehavioral Reviews, Volume 148Author(s): Dominik R. Bach, Juliana Sporrer, Rany Abend, Tom Beckers, Joseph E. Dunsmoor, Miquel A. Fullana, Matthias Gamer, Dylan G. Gee, Alfons Hamm, Catherine A. Hartley, Ryan J. Herringa, Tanja Jovanovic, Raffael Kalisch, David C. Knight, Shmuel Lissek, Tina B. Lonsdorf, Christian J. Merz, Mohammed Milad, Jayne Morriss, Elizabeth A. Phelps

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[Correspondence] A fundamental change is needed for appraising placebo responses in psychiatry

Leave a Comment / Anxiety News, Anxiety Research, Depression Research, Medicine and Anxiety, News, Physical Treatment for Anxiety /

In the Alpha-Stim Anxiety Insomnia and Depression cranial electrotherapy stimulation trial, Richard Morriss and colleagues reported no significant difference in their primary depression outcome between active and sham groups.1 Although not the headline of the article, 41% of recruited patients who received sham stimulation had remission of their depression. This remarkable result adds to the growing list of neurotechnology trials in psychiatry demonstrating very large responses in their placebo arms.

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Preoperative state anxiety predicts postoperative health-related quality of life: A prospective observational study on patients undergoing lung cancer surgery

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ObjectiveImproving quality of life (QOL) after surgery is very important. Recently, preoperative anxiety has been suggested to predict postoperative health-related (HR) QOL, however the accuracy of anxiety measurement remains problematic. We examined the relationship between preoperative anxiety level and postoperative HRQOL using qualitative and quantitative assessment of anxiety.MethodWe used a detailed anxiety assessment to quantitatively investigate preoperative anxiety as a predictor of postoperative HRQOL in lung cancer patients. Fifty one patients who underwent surgery for lung cancer were included. They were assessed four times: on admission, on discharge, 1 month after surgery, and 3 months after surgery. Anxiety was measured separately as “state anxiety” and “trait anxiety” using the State–Trait Anxiety Inventory, and HRQOL was measured using the EuroQol 5 dimension 5-level.ResultsThe HRQOL decreased at discharge and gradually recovered over time, reaching the same level at 3 months after surgery as at admission. HRQOL score was lower at discharge than at pre-surgery and 3 months after the surgery (p 

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