Astrocytes are the most common type of glial cells in the CNS. They work closely with neurons. To help understand disease, we need to know the protein networks of neurons and astrocytes. Soto et al. published a paper in Nature describing a method to identify astrocytic and neuronal proteins. They used a specific type of biotinylation to separate them from the cytosol or plasma membrane. The authors found proteins in striatal astrocytes …
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